Permanent article identifierDOI (Digital Object Identifier) We provide DOI to all published papers to facilitate higher citation and classification of articles. Peertechz Publisher ID: 10.17352
Publisher infoPeertechz Publications 10880 Wilshire Blvd., Los Angeles, California, 90024, USA (Inc.)
Kavuri Hills, Jubilee Hills, Hyderabad-500033, India (Pvt. Ltd.)
Research Interest: Leptin Receptors (Lepr) are Expressed by Various
Types of Stem Cells Including Mesenchymal Stem Cells, Hematopoietic Stem Cells,
Embryonic Stem Cells and Induced Pluripotent Stem Cells. Leptin/Lepr Signaling
is also a Central Regulator of Metabolism.
Ricardo Alaxandre de Azevedo, PhD, Graduated in Biological Science by the University ‘Santa Cecília’- Santos (Brazil) in 2002, MSc degree in Biotechology by the University of São Paulo (Brazil) in 2010, and Ph.D. in Toxinology by the Butantan Institute (Brazil) in 2014. Presently, Postdoctoral Fellow, Department Immunology, Laboratory of Tumor Immunology, University São Paulo, July 2014-current. Also occupy position of Research Scientist, and Coordinator of Biological Assays Division at ALCHEMY, RESEARCH AND DEVELOPMENT, February-current. I have experience and scientific production in the area of Apoptosis and cell cycle signaling, peptides and peptidases, molecular biology and cancer genetics, cells immunology, with emphasis on biochemotherapy and immunotherapy of cancer, focusing murine melanoma and human tumors.
Two Major Projects are Currently Underway in the Laboratory.
A Cell Reprogramming Technique Has Been Used to Convert Heterogeneous Malignant
Breast Cancer Cells into Induced Pluripotent Stem Cells Using Sox2/Oct4/Nanog
Proteins. Dr. Wu’s Laboratory is Clarifying these Induced Pluripotent Stem
Cells for their Differentiation Potential and Oncogenic Properties, and Try to
Develop a Novel Cell Converting Therapy for Malignant Breast Cancer Treatment.
Metastasis, the Spread of Cancer Cells from the Primary Tumor To Distant
Organs, Is The Most Dreadful Development Of Breast Cancer, As Well As Other
Neoplastic Diseases. Although Metastasis Contributes To Over 90% Of Human
Cancer Mortality, The Molecular Mechanism Of This Process Remains Largely
Unknown. Dr. Wu’s Laboratory Is In The Process Of Identifying Molecular
Signatures Involved In Breast Cancer Metastasis Using Integrative Genetic,
Epigenetic And Proteomic Approach, As Well As Animal Models And Clinical
Specimens.
Dr. Monther AlAlwan is a scientist at the Stem Cell and Tissue Re-engineering Program (SCTRP), King Faisal Specialist Hospital and Research Centre, as well as an Associate professor at Alfaisal University, Riyadh Saudi Arabia. He holds M.Sc. and Ph.D. in Immunology from Dalhousie University (Halifax, Canada). Dr. AlAlwan conducted a 3-years postdoctoral fellowship studying signaling in immune cells at the University of Manitoba, Canada. During his graduate studies and postdoctoral fellowship, Dr. AlAlwan made substantial contribution in the immunology field, particularly his groundbreaking discovery that highlighted the significance of the dendritic cells in the immunological synapse. After joining the SCTRP in 2007, he shifted gear to study cancer, where he identified novel mechanisms that regulate cancer metastasis and chemoresistance. Currently, he is actively involved in dissecting the molecular pathways that regulate the function of cancer stem cells and how this related to chemoresistance and metastasis. Dr. AlAlwan is an author in 20 peer-reviewed publications, has delivered several invited lectures and is a regular reviewer for various international journals.
Research Interest: Effects of Chinese Herbal Medicine on Osteogenesis
and Adipogenesis of Mesenchymal Stem Cells, Inhibitory Effects of Chinese Herbal
Medicine on RANKL-Induced Osteoclastgenesis of RAW264.7 Cells, Effect of Chinese
Herbal Medicine on Different Osteoporotic Rat Models, Establishment of the
Screening Platform for Neuro-Regenerative Chinese Herbal Medicine by Using Rat
Mesenchymal Stem Cells, Topical Application of Chinese Medicine in
Musculoskeletal Injuries, Wound Healing, Cancer Stem Cells, Neuroprotection.