ISSN: 2690-0815
International Journal of Sexual and Reproductive Health Care
Research Article       Open ijsrhccess      Peer-Reviewed

Assessment of sexuality in patients with Peyronie’s disease

Moussaab Rachid*, Gallouo M, Graiouid M, Allali S, Seffar A, Dakir M, Debbagh A and Aboutaieb R

Medical Doctor, Sexual Health Laboratory, Hassan 2 University Casablanca, Morocco
*Corresponding author: Moussaab Rachid, Medical Doctor, Sexual Health Laboratory, Hassan 2 University Casablanca, Morocco, Tel: 212645108374; E-mail:
Received: 29 January, 2020 | Accepted: 04 March, 2020 | Published: 05 March, 2020
Keywords: Erectile dysfunction; Quality of life; Peyronie’s disease

Cite this as

Rachid M, Gallouo M, Graiouid M, Allali S, Seffar A, et al. (2020) Assessment of sexuality in patients with Peyronie’s disease. Int J Sex Reprod Health Care 3(1): 001-004. DOI: 10.17352/ijsrhc.000008

Introduction: Peyronie’s disease is an acquired fibrosis of the corpora cavernosa which causes deformation of the penis and represents one of the causes of erectile insufficiency with serious consequences for the life of a couple. The diagnosis is clinical and the treatment is medico-surgical.

Objective: Evaluation of the sexuality of patients with Peyronie’s disease.

Patients and methods: This prospective study occured from February 2017 to December 2019 including patients suffering all from Peyronie’s Disease (PD). The IIEF (International Index of Erectile Function), EHS (Erection Hardness Score) and T LUE scores were used to assess erectile function and the severity of PD. The pre-established data were: Age, co-morbidities, delays, medical background, the onset mode, data from the penis examination in the flaccid state and in erection, general examination and therapeutic management.

Results: We listed 20 patients; the average age is 58.2years (39-69years). The onset was progressive in 80% of the patients; the average consultation time was 14.1 months. Deformation was the most frequent symptom in 70% of cases, followed by the coital discomfort in 50%. Intromission was accompanied by a discomfort in 60%. In 80% of patients the disease was at the sclerotic stage. Palpation of the plaque was found in 60% of patients. The IIEF score was 14,6 and 80% of patients had erectile dysfunction, 40% of which was moderate. Grade 4 EHS was predominant in 60%, pain was mild in erection in 40% case. Dyspareunia has been reported by 60% of partners. Medical treatment was prescribed for 60% of our patients, 40% of whom received medical treatment for the dysfunction.

Conclusions: PD significantly alters the sexual and relational quality of patient’s lives.


Erectile dysfunction is the most common sexual disorder reported by men, which is defined by the persistent or recurrent inability to obtain or maintain an erection allowing satisfactory sexual intercourse [1]. It represents a clinical marker of overall health and quality of a man’s life. Peyronie’s disease which is an acquired fibrosis of the corpora cavernosa which causes deformation of the penis, represents one of the causes of severe erectile insufficiency in advanced forms with loss of self-esteem, devaluation, deprivation of harmony and dynamics of the couple and the family. The psycho-social consequences of Peyronie’s disease justifies a prospective descriptive study whose aim is to assess the sexuality of patients with PD.

Patients and methods

We carried out a prospective study from February 2017 to December 2019 reporting patients consulting at the urology department of the University hospital center Ibn Rochd in Morocco. Were included in our study all male patients meeting the criteria of the definition: deformation of the penis, it’s type of curvature, narrowing, strangulation and shortening with a plaque of fibrosis of the corpora cavernosa. Were excluded all patients having a bend of the penis without fibrous plate. The exploitation of the files was done using a counting sheet, the size of our sample was 20.

The data collected were:

• Clinics: Age, background, profession, mode of occurrence.

• Data from the examination of the penis in a flaccid state and in erections and the general examination.

• Therapeutic data: We used the IIFF SCORE to assess erectile function. This is a score that assesses erectile function for 6months, it contains 5 ITEMS grouped into 5 questions rated from 1 to 5. For its interpretation: score 5 to 10, the erection disorder is qualified severe, score 11 to 15 moderate, while score 16 to 20 is judged light. The quality of the erection will be assessed by the EHS score. It is a tool for measuring erectile function which includes 4 grades. The severity of the disease will be assessed by the T LUE score. Patients who were invited to participate in the study received the relevant indications and signed informed consent and were contacted by phone.

The questionnaire and the scores were filled in French either by:

- The doctor whose mother tongue was Arabic for patients with low education needing translation.

- The patient with a high level of education but in the presence of the doctor.


Average age is about 58.2years (39-69years) the most represented average age group is 30 to 40 followed by 50-60.

Diabetes and hypertension were present respectively in 20% of cases. Only one patient reported a trauma to the penis. 20% of patients had undergone urological surgery, 80% of them it was an inguinal hernia repair. The onset was progressive in 80% of patients, and the average consultation time was 14.1 months (15days to 02years). Deformation was the most frequent symptom in 70% of cases followed by the coital gene in 50% [2].

Intromission was impossible in all our patients; it was accompanied by a gene in 60%. Premature ejaculation occurred in one patient and 80% of patients consulted at the sclerotic stage of the disease. All patients had a penis deformation during erection caused by the injection of “ prostaglandin E2” ,80% of which had a non-complex figure curvature (Figure 1) and in 20% it was a complex (Figure 2).

Palpation of the plaque was found in 60% of patients. The general examination was normal in all patients. In 80% of cases, the patients suffered from erectile dysfunction and moderate erectile dysfunction in 40% of cases, followed by severe dysfunction in 30% of cases. Grade 4 was predominant in 60% followed by grades 1 and 2. The average score was 4.1, pain was mild at erection in 40%, and mild at coitus in 20%. In 60% the degree of curvature was 15°. Half of our patients had a 1cm plate and 10% was 2cm. Dyspareunia was reported by 60% of partners. Medical treatment was prescribed in 60% of our patients, 40% of them received medical treatment for erectile dysfunction. Resumption of normal sexual activity noted in all treated patients.


The prevalence of Peyronie’s disease is a challenge, it varies from 0.3 to 13% depending on age, geographic location, co-morbidities and socioeconomic status [1-4]. the average age varies between 48, 9 and 57.4 years [5-7]. This later was slightly higher in our study (about 58.2years) compared to the literature data and the most represented age group is that of 30 to 40. The insidious onset in 80% of patients, and the average delay of consultation late at 14.1 months would explain this. The taboo nature of the disease and the ignorance of this affection might also explain the delay in treatment. Epidemiological studies have objectified the association of PD and cardiovascular risk factors such as diabetes, hypertension, dyslipidemia, chronic smoking [8,9]. This is how Carlo and Al [10], in Italy in 2015 found diabetes to have 21% frequency, 57% hypertension and Tobacco 64%. Shiaraishi and Japan [11], reported diabetes, hypertension and tobacco respectively in 32.5%, 58% and 24%. The pathophysiology of this condition is poorly understood and multifactorial [12-14].

* Traumatic factors: Internal iterative microtrauma following prolonged erection and external following penetration difficulties, one in ten of our patients had reported trauma by direct kick on the penis.

* Genetic and hereditary factors.

* Immune factors.

* Metabolic factor.

The diagnosis of PD is clinical and is described in two phases [15,16]:

An early one: Inflammatory where the patient presents a penis nodule, a painful erection or a deformation.

− A delate one: The nodule perceived very hard, the deformation is stable, the pain has most often disappeared and sometimes the erectile dysfunction too.

The clinical examination is done in a flaccid state and in erection, it allows to palpate and locate the nodule it appreciates the degree of curvature on the three space planes. Deformation was the most frequent symptom in our study in 70% in the flaccid state and 100% in the erection caused by the injection of the “Prostaglandin E2”, 80% of which had a non-complex curvature, these data are similar to those in the literature where the curvature varies from 65 to 100% [17,18]. The deformation occurs next to the fibrous plaque or nodule [19]. The intensity and severity of this pain varies depending on the duration of the disease, the extent of the alteration of the penile shape and different positions around sexual intercourse [20]. Erection or coitus pain can reveal the disease, its intensity varies from a simple discomfort to permanent pain even in a flaccid state, in our study the frequency was 50%. This corroborates with data from other studies where the pain varies 33%-72% [4,21,22]. Penile induration is found in patients who consult only in the late phase where the curvature is manifest (Paraclinical examinations have no place in the diagnosis, the clinic is sufficient). However, ultrasound can visualize a hyperechoic plaque of the albuginea, specify their number, location and size, but the intra-cavernous doppler makes it possible to carry out the vascular assessment of erectile dysfunction [23]. MRI gives more precision on the plaque, appreciates better the non-palpable cavernous bodies, the enhancement after injection of gadolinium reflects possible inflammation, the interest lies in the therapeutic choice. Peyronie’s disease is often associated with erectile dysfunction [24].

The penetration capacity can be interfered by the curvature or the deformation resulting in erectile dysfunction [17]. This is how Rodrigeuez V, et al., [25], objectified a rate of 65% suffering from erectile dysfunction due to a difficult or impossible penetration. Walsh, et al., [26], reported 36.8% of sexual dysfunction related to curvature and shortening. Dysfunction was found in 80% of our patients. Pain and curvature in more than half of our patients would explain this erectile insufficiency. The treatment of PD includes both medical and surgical approaches. Different therapeutic options available to the patient include monitoring, topical or intralesional medication, mechanical therapy, and surgery [27], which is reserved for sequels of the inflammation phase. The limitations of this study are mainly related to its retrospective nature. We must therefore deplore a certain number missing data as well as the follow-up of certain patients who were lost to see.


Peyronie’s disease seems to seriously affect the quality of life of patients, particularly in its sexual component. These sexual disorders can be linked on one hand to the affection itself and the anxiety created by its symptoms and on the other hand to the patient by cardiovascular risk factors.

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© 2020 Rachid M, et al. This is an open-ijsrhccess article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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